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A retrospective study on the diagnosis of clostridial myonecrosis in ruminants in Brazil Ciência Rural
Pires,Prhiscylla Sadanã; Ecco,Roselene; Silva,Rodrigo Otávio Silveira; Araújo,Marina Rios de; Salvarani,Felipe Masiero; Heneine,Luíz Guilherme Dias; Oliveira Júnior,Carlos Augusto de; Lobato,Francisco Carlos Faria.
ABSTRACT: A standardized immunochemistry method for the diagnosis of clostridial myonecrosis was applied to 38 formalized tissue samples from ruminants with clinical and post mortem history suggestive of blackleg or gas gangrene. The diagnosis of clostridial myonecrosis was confirmed in 37 out of 38 (97.4%) samples tested. Clostridium chauvoei and Clostridium perfringens type A were the most common agents found alone, being detected in ten (26.3%) and six (15.8%) samples, respectively. The other cases showed an association of two or three clostridia, with C. perfringens type A detected in 11 (29%) cases. Based on the findings of the present study, polyvalent vaccines against clostridial infections of animals incorporating C. perfringens would be more...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gas gangrene; Blackleg; Malignant edema; Cattle; Sheep; Immunohistochemistry.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000100452
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Botulism in non-ruminants in Brazil Ciência Rural
Oliveira Júnior,Carlos Augusto de; Silva,Rodrigo Otávio Silveira; Olinda,Roberio Gomes; Lobato,Francisco Carlos Faria.
ABSTRACT: Botulism is an intoxication caused by the ingestion of neurotoxins secreted by Clostridium botulinum and characterized by progressive flaccid symmetrical paralysis. Among non-ruminant animals, avian species and dogs are the most commonly affected by botulism, while horses and pigs are less-commonly diagnosed with the disease. Despite the importance of this disease in animals, the Brazilian literature only includes case studies and outbreak descriptions. The aim of this study was to review the main features and to provide recent data on the occurrence of botulism in non-ruminants in Brazil.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Flaccid paralysis; Clostridium botulinum; Avian; Dogs; Horses; Pigs.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001202158
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Pesquisa utiliza microrganismo Clostridium difficile para prevenir infecções em hamsters Ciência Rural
Oliveira Júnior,Carlos Augusto de.
Tipo: Info:eu-repo/semantics/other
Ano: 2024 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016010700002
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Prevention of Clostridium difficile infection in hamsters using a non-toxigenic strain Ciência Rural
Oliveira Júnior,Carlos Augusto de; Silva,Rodrigo Otávio Silveira; Diniz,Amanda Nádia; Pires,Prhiscylla Sadanã; Lobato,Francisco Carlos Faria; Assis,Ronie Antunes de.
ABSTRACT: The present study aimed to evaluate five non-toxigenic strains of Clostridium difficile (NTCD) in vitro and to select one strain to prevent C. difficile (CDI) infection in hamsters ( Mesocricetus auratus ). The NTCD strains were evaluated for spore production in vitro, antimicrobial susceptibility and presence of antimicrobial resistance genes. Approximately 107 spores of the selected strain (Z31) were administered by esophageal gavage in hamsters pretreated with 30mg kg-1 of clindamycin. The challenge with a toxigenic strain of C. difficile was conducted at 36 and 72h, and the animals were observed for 28 days. The NTCD strain of C. difficile (Z31) was able to prevent CDI in all animals that received it.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diarrhea; Clostridium difficile- associated diseases; Colitis.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016000500853
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